Diazoxide and its Tautomers - A DFT Treatment

Diazoxide have several potential effectors that may potentially contribute to cardio protection. It is used manage symptoms of hypoglycemia caused by pancreas cancer, surgery, or other conditions. also acts as a non-diuretic antihypertensive agent. possessing various tautomeric forms should display variable biological properties depending on its tautomer content. exhibit 1,3- and 1,5-type proton tautomerism. Presently, all those possible are considered. All the calculations been performed within realm density functional theory with constraints B3LYP/6-311++G(d,p) level. tautomers electronically stable thermo chemically favorable formation values at standard Some quantum chemical spectral systems well nucleus-independent shift (NICS) obtained discussed.